Document Type : Original Article

Authors

1 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Shahid Rajaee Teacher Training

2 Department of sport Physiology, Faculty of Sport Sciences, Shahid Rajaei University, Tehran, Iran

3 Professor of exercise physiology,Department of exercise physiology,Faculty of sport science in tehran Shahid rajaee teacher training university

10.22089/jehs.2023.14029.1060

Abstract

The COVID-19 pandemic has created the largest disruption of students’ physical activity and threatens of immune system in the century. Although quarantine can be considered to fight against CORONA, its negative effects are certainly undeniable. Methods: The present study was a semi-experimental study in a pre-posttest design with a control group. The participant students (16.1±1.26 years old; n = 30) were randomly divided into the experimental group (CEP, n = 15) and the non-exercising control group (CG, n = 15). The pre/post assessment included: (1) salivary immunoglobulin-A (sIgA); (2) functional capacity (Muscular endurance, Flexibility, and cardiovascular endurance). After proving the normality of data distribution using Kolmogorov-Smirnov test, analysis of covariance (ANCOVA) was used to evaluate the effectiveness of the exercises and Leven’s test was used to prove the assumption of homogeneity of variance. Results: The results revealed a significant (p = 0.045) increase in s-IgA levels after CEP. In control group s-IgA increased moderately and was not significant. Robust statistical differences observed in Muscular endurance, flexibility, and Vo2peak (p < 0.05) in experimental group. Conclusion: Body weight strength training is an effective program to improve functional capacity and immune system of students during COVID-19. It can be an available training program which can carried out in home. Although more research is needed to specify the relation of sport immunology and students kept in quarantine. Due to the possibility of closing schools in extraordinary circumstances such as the Corona pandemic or air pollution in densely populated cities such as Tehran.

Keywords

  1. Ahmadi Hekmatikar, A. H., & Molanouri Shamsi, M. (2020). Effect of Exercise on Immunological Indicators During the COVID-19 Pandemic. Journal of Arak University of Medical Sciences, 23(5), 584-603. doi:10.32598/jams.23.Cov.6277.1
  2. Ahn, N., & Kim, K. (2018). The effects of resistance elastic bands exercises on salivary IgA and salivary cortisol levels in elderly women. Biomedical Research (0970-938X), 29(5).
  3. Akimoto, T., Kumai, Y., Akama, T., Hayashi, E., Murakami, H., Soma, R., . . . Kono, I. (2003). Effects of 12 months of exercise training on salivary secretory IgA levels in elderly subjects. British journal of sports medicine, 37(1), 76-79.
  4. Ayala, F., de Baranda, P. S., Croix, M. D. S., & Santonja, F. (2012). Reproducibility and criterion-related validity of the sit and reach test and toe touch test for estimating hamstring flexibility in recreationally active young adults. Physical Therapy in Sport, 13(4), 219-226.
  5. Azzi, L., Dalla Gasperina, D., Veronesi, G., Shallak, M., Ietto, G., Iovino, D., . . . Focosi, D. (2022). Mucosal immune response in BNT162b2 COVID-19 vaccine recipients. EBioMedicine, 75, 103788.
  6. Blannin, A., Robson, P., Walsh, N., Clark, A., Glennon, L., & Gleeson, M. (1998). The effect of exercising to exhaustion at different intensities on saliva immunoglobulin A, protein and electrolyte secretion. International journal of sports medicine, 19(08), 547-552.
  7. Bodyweight Strength Training: 12 Weeks to Build Muscle and Burn Fat. (2017). Rockridge Press; Illustrated edition (December 19, 2017).
  8. Borg, G. (1982). A category scale with ratio properties for intermodal and interindividual comparisons. Psychophysical judgment and the process of perception, 25-34.
  9. Buresh, R., Berg, K., & French, J. (2009). The effect of resistive exercise rest interval on hormonal response, strength, and hypertrophy with training. J Strength Cond Res, 23(1), 62-71. doi:10.1519/JSC.0b013e318185f14a
  10. Chao, Y. X., Rötzschke, O., & Tan, E. K. (2020). The role of IgA in COVID-19. Brain Behav Immun, 87, 182-183. doi:10.1016/j.bbi.2020.05.057
  11. Chen, P., Mao, L., Nassis, G. P., Harmer, P., Ainsworth, B. E., & Li, F. (2020). Coronavirus disease (COVID-19): The need to maintain regular physical activity while taking precautions. Journal of Sport and Health Science, 9(2), 103-104. doi:https://doi.org/10.1016/j.jshs.2020.02.001
  12. Contreras, B. (2013). Bodyweight strength training anatomy: Human Kinetics.
  13. Cooper, K. (1968). A means of assessing maximal oxygen intake. Jama, 203, 135-138.
  14. Dimitriou, L., Sharp, N., & Doherty, M. (2002). Circadian effects on the acute responses of salivary cortisol and IgA in well trained swimmers. British journal of sports medicine, 36(4), 260-264.
  15. Drummond, L. R., Campos, H. O., Drummond, F. R., de Oliveira, G. M., Fernandes, J. G. R. P., Amorim, R. P., . . . Coimbra, C. C. (2022). Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis. Pflügers Archiv - European Journal of Physiology, 474(12), 1221-1248. doi:10.1007/s00424-022-02760-1
  16. Engels, H.-J., Kendall, B. J., Fahlman, M. M., Gothe, N. P., & Bourbeau, K. C. (2017). Salivary immunoglobulin A in healthy adolescent females: effects of maximal exercise, physical activity, body composition and diet. The Journal of sports medicine and physical fitness, 58(7-8), 1096-1101.

 

 

  1. Fornieles, G., Rosety, M., Elosegui, S., Rosety, J., Alvero-Cruz, J., Garcia, N., . . . Rosety-Rodriguez, M. (2014). Salivary testosterone and immunoglobulin A were increased by resistance training in adults with Down syndrome. Brazilian Journal of Medical and Biological Research, 47, 345-348.
  2. Gaeini, A., Pari, F., Mohammad, F., & Azar, J. (2013). Acute Effects of One, Two and Three Bouts of Physical Education Lessons
  3. in Week on Salivary IgA and Salivary Cortisol of School
  4. sport physiology and managment investigation, year4(4), 45-.
  5. Garber, C. E., Blissmer, B., Deschenes, M. R., Franklin, B. A., Lamonte, M. J., Lee, I.-M., . . . Swain, D. P. (2011). Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise.
  6. GHAHRAMANLOU, E., AGHA, A. H., & Gharakhanlou, R. (2008). EFFECTS OF STRENGTH, ENDURANCE AND CONCURRENT TRAINING ON BIOENERGETICS'CHARACTERISTICS, MAXIMUM STRENGTH AND BODY COMPOSITION IN UNTRAINED MEN.
  7. Gorostiaga, E. M., Izquierdo, M., Ruesta, M., Iribarren, J., González-Badillo, J. J., & Ibáñez, J. (2004). Strength training effects on physical performance and serum hormones in young soccer players. Eur J Appl Physiol, 91(5-6), 698-707. doi:10.1007/s00421-003-1032-y
  8. Hammami, A., Harrabi, B., Mohr, M., & Krustrup, P. (2022). Physical activity and coronavirus disease 2019 (COVID-19): specific recommendations for home-based physical training. Managing Sport and Leisure, 27(1-2), 26-31.
  9. Han, P., & Ivanovski, S. (2020). Saliva—Friend and Foe in the COVID-19 Outbreak. Diagnostics, 10(5), 290. Retrieved from https://www.mdpi.com/2075-4418/10/5/290
  10. Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., . . . Nitsche, A. (2020). SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. cell, 181(2), 271-280. e278.
  11. Hosseini, M, Rostami, R, Farzanegi, P, & Esteghamati, A. (2009). Effect of Resistance and Endurance Trainings on Salivary Immunoglobulin A, Cortisol and Dehydroepiandrosterone Concentration in Untrained Females. Journal of Babol University Of Medical Sciences, 11(5), 38-44. Retrieved from http://jbums.org/article-1-3360-fa.html
  12. Isho, B., Abe, K. T., Zuo, M., Jamal, A. J., Rathod, B., Wang, J. H., . . . Bang, Y. M. (2020). Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Science immunology, 5(52), eabe5511.
  13. Javadinezhad, S., Nasiri, E., & Samadi, A. (2022). Comparison of the Effect of 8 Weeks of Continuous, Intermittent Training on Maximum Oxygen Consumption, Muscle Endurance and General Health of Overweight Seventh Grade Male Students. Pajouhan Scientific Journal, 20(4), 250-259. Retrieved from http://psj.umsha.ac.ir/article-1-856-fa.html

 

  1. Kiess, W., Meidert, A., Dressendörfer, R., Schriever, K., Kessler, U., Köunig, A., . . . Strasburger, C. (1995). Salivary cortisol levels throughout childhood and adolescence: relation with age, pubertal stage, and weight. Pediatric research, 37(4), 502-506.
  2. Koch, A. J., Wherry, A. D., Petersen, M. C., & Johnson, J. C. (2007). Salivary immunoglobulin A response to a collegiate rugby game. Journal of strength and conditioning research, 21(1), 86.
  3. Kumar, P., Kumar, M., Bedi, O., Gupta, M., Kumar, S., Jaiswal, G., . . . Jamwal, S. (2021). Role of vitamins and minerals as immunity boosters in COVID-19. Inflammopharmacology, 29(4), 1001-1016. doi:10.1007/s10787-021-00826-7
  4. Levine, B. D. (2008). : what do we know, and what do we still need to know? The Journal of physiology, 586(1), 25-34.
  5. Lima, M. S., Ribeiro, P. P., Medeiros, J., Silva, I. F., Medeiros, A. C., & Dimenstein, R. (2012). Influence of postpartum supplementation with vitamin A on the levels of immunoglobulin A in human colostrum. Jornal de pediatria, 88, 115-118.
  6. Marques-Feixa, L., Castro-Quintas, Á., Palma-Gudiel, H., Romero, S., Morer, A., Rapado-Castro, M., . . . Marín-Vila, M. (2022). Secretory immunoglobulin A (s-IgA) reactivity to acute psychosocial stress in children and adolescents: The influence of pubertal development and history of maltreatment. Brain, behavior, and immunity, 103, 122-129. doi:https://doi.org/10.1016/j.bbi.2022.04.010
  7. McManus, A. M., Cheng, C. H., Leung, M. P., Yung, T. C., & Macfarlane, D. J. (2005). Improving aerobic power in primary school boys: a comparison of continuous and interval training. Int J Sports Med, 26(9), 781-786. doi:10.1055/s-2005-837438
  8. Meselson, M. (2020). Droplets and Aerosols in the Transmission of SARS-CoV-2. N Engl J Med, 382(21), 2063. doi:10.1056/NEJMc2009324
  9. Moore, S. A., Faulkner, G., Rhodes, R. E., Brussoni, M., Chulak-Bozzer, T., Ferguson, L. J., . . . Tremblay, M. S. (2020). Impact of the COVID-19 virus outbreak on movement and play behaviours of Canadian children and youth: a national survey. Int J Behav Nutr Phys Act, 17(1), 85. doi:10.1186/s12966-020-00987-8
  10. Nieman, D., Henson, D., Fagoaga, O., Utter, A., Vinci, D., Davis, J., & Nehlsen-Cannarella, S. (2002). Change in salivary IgA following a competitive marathon race. International journal of sports medicine, 23(01), 69-75.
  11. Nussbaumer-Streit, B., Mayr, V., Dobrescu, A. I., Chapman, A., Persad, E., Klerings, I., . . . Gartlehner, G. (2020). Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review. Cochrane Database Syst Rev, 4(4), Cd013574. doi:10.1002/14651858.Cd013574
  12. Peçanha, T., Goessler, K. F., Roschel, H., & Gualano, B. (2020). Social isolation during the COVID-19 pandemic can increase physical inactivity and the global burden of cardiovascular disease. American Journal of Physiology-Heart and Circulatory Physiology.
  13. Pilette, C., Ouadrhiri, Y., Godding, V., Vaerman, J.-P., & Sibille, Y. (2001). Lung mucosal immunity: immunoglobulin-A revisited. European Respiratory Journal, 18(3), 571-588.
  14. Ribeiro, B., Forte, P., Vinhas, R., Marinho, D. A., Faíl, L. B., Pereira, A., . . . Neiva, H. P. (2022). The Benefits of Resistance Training in Obese Adolescents: A Systematic Review and Meta-analysis. Sports Medicine-Open, 8(1), 1-12.
  15. Shakeri N, N. H., Azarbayjani M, Amirtash A. (2012). The effect of different types of exercise on the testosterone/cortisol ratio in untrained young males. Journal of Practical Studies of Biosciences in Sport, 2012;22:21-7.
  16. Siavoshy, H. (2016). Effects of resistance training on salivary hormone profile and immunoglobulin a in adults with Down syndrome. Exceptional Education, 9(137), 60-64.
  17. Stokes, C. R., Soothill, J. F., & Turner, M. W. (1975). Immune exclusion is a function of IgA. Nature, 255(5511), 745-746. doi:10.1038/255745a0
  18. Talebi, K., Hejazi, S. M., Mottaghi, M. R., Basiry Moqadam, M., Irani, H., & Gholami Koopaie, M. (2013). Effect of intense exercise on the concentration of immunoglobulin A and salivary cortisol in swimmers. Internal Medicine Today, 18(4), 191-196. Retrieved from http://imtj.gmu.ac.ir/article-1-1476-fa.html
  19. Varadhachary, A., Chatterjee, D., Garza, J., Garr, R. P., Foley, C., Letkeman, A., . . . Traylor, R. (2020). Salivary anti-SARS-CoV-2 IgA as an accessible biomarker of mucosal immunity against COVID-19. medRxiv.
  20. Werner, W., & Sharon, A. (2011). Lifetime physical fitness and wellness. Wadsworth: United State of America.
  21. Windarwati, H. D., Lestari, R., Supianto, A. A., Wicaksono, S. A., Ati, N. A., Kusumawati, M. W., . . . Ekawati, D. (2022). A narrative review into the impact of COVID‐19 pandemic on senior high school adolescent mental health. Journal of Child and Adolescent Psychiatric Nursing.
  22. Xiang, M., Zhang, Z., & Kuwahara, K. (2020). Impact of COVID-19 pandemic on children and adolescents' lifestyle behavior larger than expected. Prog Cardiovasc Dis, 63(4), 531-532. doi:10.1016/j.pcad.2020.04.013
  23. Zheng, Y., Li, H., Gao, K., & Gallo, P. M. (2022). Developing a Home-Based Body Weight Physical Activity/Exercise Program. ACSM's Health & Fitness Journal, 26(2), 20-28. doi:10.1249/fit.0000000000000746
  24. Zhou, P., Yang, X. L., Wang, X. G., Hu, B., Zhang, L., Zhang, W., . . . Shi, Z. L. (2020). A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 579(7798), 270-273. doi:10.1038/s41586-020-2012-7